Locus 255

GWAS results
Target annotations
Locus annotations
Network

Top associations per target

Target	cis/trans	Study	SNP	SNP location	Maj/min allele	MAF	N	β_inv	se_inv	P_inv	fc_log	P_log	P_raw
PPAC	cis	Discovery	rs12475664	2:309,097	C/A	0.36	990	0.374	0.045	4.6×10^-16	1.300	1.9×10^-16	2.3×10^-16
PPAC	cis	Replication	rs12475664	2:309,097	C/A	0.38	337	0.253	0.062	5.2×10^-5	1.300	2.9×10^-6	4.2×10^-6

Regional association plots

Low molecular weight phosphotyrosine protein phosphatase (PPAC)

Download the association data used to generate this plot

Boxplots and histograms for top associations

Low molecular weight phosphotyrosine protein phosphatase (PPAC)

	inverse-normalized probe levels	log₂ transformed probe levels	raw probe levels
Discovery study
Replication study

Low molecular weight phosphotyrosine protein phosphatase (PPAC)

Target (abbrv.)	PPAC
Target (full name)	Low molecular weight phosphotyrosine protein phosphatase
Somalogic ID (Sequence ID)	SL008063 (3858-5_1)
Entrez Gene Symbol	ACP1
UniProt ID	P24666
UniProt Comment	Acts on tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates. Isoform 3 does not possess phosphatase activity.
Pathway Interaction Database	EPHA2 forward signaling

All locus annotations are based on the sentinel SNP (rs12475664).
Download the detailed results of SNiPA's block annotation (PDF)

Linked genes

Genes hit or close-by