Locus 370

GWAS results
Target annotations
Locus annotations
Network

Top associations per target

Target	cis/trans	Study	SNP	SNP location	Maj/min allele	MAF	N	β_inv	se_inv	P_inv	fc_log	P_log	P_raw
KI2L4	cis	Discovery	rs7259090	19:55,392,646	G/A	0.17	997	0.413	0.057	1.3×10^-12	1.110	2.4×10^-7	0.652

Regional association plots

Killer cell immunoglobulin-like receptor 2DL4 (KI2L4)

Download the association data used to generate this plot

Boxplots and histograms for top associations

Killer cell immunoglobulin-like receptor 2DL4 (KI2L4)

	inverse-normalized probe levels	log₂ transformed probe levels	raw probe levels
Discovery study

Killer cell immunoglobulin-like receptor 2DL4 (KI2L4)

Target (abbrv.)	KI2L4
Target (full name)	Killer cell immunoglobulin-like receptor 2DL4
Somalogic ID (Sequence ID)	SL012698 (5095-21_3)
Entrez Gene Symbol	KIR2DL4
UniProt ID	Q99706
UniProt Comment	Receptor on natural killer (NK) cells for HLA-C alleles. Inhibits the activity of NK cells thus preventing cell lysis.
Reactome	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Pathway Studio	Natural Killer Cell Activation through Integrins and non-ITAM-Containing Receptors

All locus annotations are based on the sentinel SNP (rs7259090).
Download the detailed results of SNiPA's block annotation (PDF)

Linked genes

Genes hit or close-by

FCAR Fc fragment of IgA, receptor for