Locus 428

GWAS results
Target annotations
Locus annotations
Network

Top associations per target

Target	cis/trans	Study	SNP	SNP location	Maj/min allele	MAF	N	β_inv	se_inv	P_inv	fc_log	P_log	P_raw
Siglec-6	cis	Discovery	rs35931837	19:52,033,158	C/T	0.11	995	-0.481	0.072	3.6×10^-11	-1.050	0.118	0.038

Regional association plots

Sialic acid-binding Ig-like lectin 6 (Siglec-6)

Download the association data used to generate this plot

Boxplots and histograms for top associations

Sialic acid-binding Ig-like lectin 6 (Siglec-6)

	inverse-normalized probe levels	log₂ transformed probe levels	raw probe levels
Discovery study

Sialic acid-binding Ig-like lectin 6 (Siglec-6)

Target (abbrv.)	Siglec-6
Target (full name)	Sialic acid-binding Ig-like lectin 6
Somalogic ID (Sequence ID)	SL005217 (2741-22_2)
Entrez Gene Symbol	SIGLEC6
UniProt ID	O43699
UniProt Comment	Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.

All locus annotations are based on the sentinel SNP (rs35931837).
Download the detailed results of SNiPA's block annotation (PDF)

Linked genes

Genes hit or close-by

SIGLEC6 sialic acid binding Ig-like lectin 6